Arsene Wenger feels Arsenal will get their season back on track against Manchester United on Saturday.
Arsenal have not won in three games after following up their draw with Tottenham and defeat to Stoke with a stalemate against Fenerbahce in the Champions League.
The Gunners' stuttering form has seen them slip six points behind joint Premier League leaders Chelsea and Liverpool, but Wenger remains upbeat going into their first meeting with one of the other 'big four' this season.
"It is a massive game and of massive importance for us. We play every three days at the moment and every game is massive for us," the Frenchman told the club's official website.
"Manchester United-Arsenal is always a special one and we know for us it is vital to do well in the big games in this league.
"I am confident we will."
United will also be keen to narrow the five-point gap to the leading pair and go into the clash having all but secured their place in the Champions League knockout stages with a draw against Celtic on Wednesday.
Chelsea captain John Terry has called on his side to bounce back from their midweek loss to Roma when they take on Blackburn on Sunday.
The Blues lost 3-1 in the Italian capital to a side who had gone into the match on the back of five straight defeats.
"The (Roma) result is maybe a kick up the backside that we needed," he told Chelsea TV.
"Maybe we need to realise we are not the best side that we thought we were."
Liverpool's task looks, on paper at least, somewhat easier as they put their unbeaten home record on the line against West Brom on Saturday.
On Sunday, Tottenham will aim to continue their recent revival under new coach Harry Redknapp.
The former Portsmouth boss has guided the Londoners to wins over Bolton and Liverpool - as well as that draw with Arsenal - in his first three games in charge.
They still prop up the table, though, two points separating them from safety, and travel to face a Manchester City looking to boost their European hopes.
Elsewhere on Saturday, Hull will aim to bounce back from consecutive defeats at home to Bolton, Tony Adams goes in search of his first point as Portsmouth boss when he takes his side to Sunderland, West Ham host Everton and Wigan meet Stoke.
On Sunday, Aston Villa are up against Middlesbrough and Newcastle travel to Fulham looking to make it three wins in a row.
